Basic Information
VIS ID
TVIS44023488
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
34253059/33678922 (Hg38)
End
34253059/33678922 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/9516418; hsa-mir-1267/Downstream/5985112;
Nearest TSS
ENST00000623511/Upstream/2154; ENST00000380071/Downstream/139127;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/135919, chr13-CpG: 38/Downstream/139068
Nearby gene
STARD13(-2087) ;
Nearest cancer related gene
STARD13(TSG, -2087) ;
Upstream sequence
gcagtgagctgagactgtgccactgcactccagcctgggtggcagagcaagactctcaaaaaaagaaaCTGTCTTTTGGGATATTAAAAGGCCAAGGTAG
Downstream sequence
GACTTCATGAAGAAGCTGTACCCAATACTTTTGTAGTGAAATTGAGCACTCTTGTTTCTCTTCTTCATGGTGATGACCTCATGACTGATGACCTCATGTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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