Basic Information
VIS ID
TVIS44023521
Fusion event
HTLV-1-LINC00358 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
62587569/62013436 (Hg38)
End
62587569/62013436 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA13B
Target gene
LINC00358
Nearest miRNA
hsa-mir-1297/Upstream/813556; hsa-mir-1267/Downstream/3952894;
Nearest TSS
ENST00000623511/Upstream/585490; ENST00000455977/Downstream/16112;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1615525, chr13-CpG: 36/Downstream/1798150
Upstream sequence
agtttgctttgtttgatcaacaggAAGAATGCTCAAGCTATAAATGAGAACAAAATAATTTTATATGGTTAACCTTTGCTATTAATGATTTTGAAACTTG
Downstream sequence
ATATTAATTGTCCTTAATGCATCATCACTTGACAAGACAATCTAACAGCATAAGTAGAGAGATATAAATATTCCATATTTGAACAAAGCAACCCTAAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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