Basic Information
VIS ID
TVIS44023536
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
72637705/72063567 (Hg38)
End
72637705/72063567 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/5845243; hsa-mir-1267/Downstream/5634445;
Nearest TSS
ENST00000623511/Upstream/196375; ENST00000618209/Downstream/664120;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/195923, chr13-CpG: 91/Downstream/663525
Nearby gene
DACH1(-196375) ;
Nearest cancer related gene
DACH1(TSG, -196375) ;
Upstream sequence
ggtgggtaataacaaactcctctgagccataatgcaaggaagctaagaactttgaataaaggttagacaaattgttaactagaataacagcatagagaag
Downstream sequence
aacataaatgacctgatggagctgaaaaacacagcatgagaatgtcatgaagcatacgcaagtatcaatagccaaatcaatcaagcagaagaaaggatat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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