Basic Information
VIS ID
TVIS44023557
Fusion event
HTLV-1-GPC5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
End
92071433/91419179 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1297/Upstream/67788; hsa-mir-1267/Downstream/1070984;
Nearest cancer related gene
GPC5(TSG, No orient, 0)
Upstream sequence
TTATGCTGTAGGACCCTTTTATTACTATACAAGTTATAAAACTTCAAGAATAGCTAATAATTTGAGCAAGAAGGAATCAAGCAATTCAATGTCTTAATAG
Downstream sequence
TTTCCAGTTAGCTATAGCTTTCTATTTTATGTGAATTTATATTCTAGCTCTTTTGATATTAGTTTAAATGAATGTACAGAGATTCATATAATCTGAAAAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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