Basic Information
VIS ID
TVIS44023568
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
104909766/104443429 (Hg38)
End
104909766/104443429 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1185-1/Upstream/325915; hsa-mir-12121/Downstream/234265;
Nearest TSS
ENST00000550708/Upstream/64478; ENST00000331952/Downstream/136255;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12157, chr14-CpG: 30/Downstream/17675
Nearby gene
C14orf180(No orient, 136255)
Upstream sequence
GAGGCTTTCCCAGGCAGCAGGCCCCTTGCTTTCCGGGGCCCAGTGGCAGCTGCAGAGCAGGGCAGGCTCAGGCTGGTCTGGAAGCCCCTGCCCCTCACCT
Downstream sequence
GCTGGAAGGCTGCTCTCCTCCAGAGCAGATCTGGTCCTTCCAGAAGCCTCCTCCTCCCCACCCAGCAGGGCTCTGCAGGCCTCCCCCTGCCTCAGGCTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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