VISDB Viral Integration Site DataBase

VIS ID

TVIS44023571

Fusion event

HTLV-1-PACS2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q32.33

Reference genome

Start

End

105815029/105348692 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-222-3p ; hsa-let-7e-5p ; hsa-mir-133a-3p ; hsa-mir-4281 ; hsa-mir-1289 ; hsa-mir-1252-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4726-3p ; hsa-mir-4308 ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-125a-3p ; hsa-mir-2114-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-6868-3p ; hsa-mir-7977 ; hsa-mir-6815-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-149-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-6771-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7153-5p ; hsa-mir-1827 ; hsa-mir-146b-5p ; hsa-mir-4649-3p ; hsa-mir-146a-5p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p

Nearest miRNA

hsa-mir-1185-1/Upstream/197828; hsa-mir-4507/Downstream/272424;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/18280, chr14-CpG: 22/Downstream/2274

Upstream sequence

GTGACCCCGGCTGTGGCTGGGTGCTGTGTAGGCTTTCCATGTGCCTGGGAGACGAGTCAGGCGGTGCGCTACTGTGGGGCCTTGTGCCAAAACAGCGGGC

Downstream sequence

AGCCCATGCCATCTCCGGGAGCCCGGGGGGCTGGGAATGACAGGATGCTCCTGGGTCCAGTCCTGTCCCGCACAAGGGAGGCAGGCCCGGCCTTCTGGGA