Basic Information
VIS ID
TVIS44023590
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
28602577/28133371 (Hg38)
End
28602577/28133371 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/500093; hsa-mir-1185-1/Downstream/2881275;
Nearest TSS
ENST00000550708/Upstream/499246; ENST00000548280/Downstream/184770;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1928099, chr14-CpG: 203/Downstream/632312
Nearby gene
LINC00645(No orient, 493735)
Upstream sequence
AAATTGGAAGAAATTCCACTGAATTTTTGAAGATGTTATGGCAAATATTTTAAAAAATTATGAAAGCCTGCTAGTTACTGAAATTGTCAGATATAGCTTC
Downstream sequence
CTTGTGTTATTCTTTTGTAGTTGAATACTTATCAATATACTACAAAATTTGATCTGAAATATTTCAAGGAAATGCTTTGTTGTAAACTACCTCAAATCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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