VISDB Viral Integration Site DataBase

VIS ID

TVIS44023596

Fusion event

HTLV-1-G2E3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q12

Reference genome

Start

End

31033949/30564743 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-186-5p ; hsa-mir-125a-5p ; hsa-let-7a-5p ; hsa-mir-9-3p ; hsa-mir-548v ; hsa-mir-548au-3p ; hsa-mir-6509-5p ; hsa-mir-511-5p ; hsa-mir-5701 ; hsa-mir-331-5p ; hsa-mir-585-5p ; hsa-mir-5682 ; hsa-mir-6830-3p ; hsa-mir-582-5p ; hsa-mir-5681b ; hsa-mir-935 ; hsa-mir-4678 ; hsa-mir-5003-3p ; hsa-mir-6739-3p ; hsa-mir-375 ; hsa-mir-921 ; hsa-mir-3606-5p ; hsa-mir-8068 ; hsa-mir-3682-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-1272 ; hsa-mir-708-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-208a/Upstream/2931465; hsa-mir-1185-1/Downstream/449903;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/5137, chr14-CpG: 122/Downstream/309406

Upstream sequence

cattttaaagtagacatttcagtgacagtacattcacgatgttgtgcaaccatcacctctacctagttccaaaacatgtaaccttttatgtctgacttcc

Downstream sequence

ctcatttaatataatgttttcaaggttatctatgttgtagcatgtttcagtactttattcctttttattgccacataatcattctatggatataccacat