Basic Information
VIS ID
TVIS44023608
Fusion event
HTLV-1-LOC105370456 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38499860/38030655 (Hg38)
End
38499860/38030655 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105370456
Nearest miRNA
hsa-mir-208a/Upstream/1078264; hsa-mir-1185-1/Downstream/9730340;
Nearest TSS
ENST00000550708/Upstream/25808; ENST00000555655/Downstream/60503;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/407684, chr14-CpG: 43/Downstream/177294
Nearby gene
SSTR1(+177344) ;
Upstream sequence
tcagtggaacggttgtagatgtgaggcaagcagcatctgaacagaagctttaaatgagcttgtgtgatttttctccctttacccttaacatttccctcta
Downstream sequence
ccatgggaacaccatgccctaggcagtggccactacttaattctggatctcggGACAAGTAGCCATACAAGAATGGCCCACTGGACCTAGTGCAGCCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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