Basic Information
VIS ID
TVIS44023622
Fusion event
HTLV-1-LINC01599 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50485348/50018630 (Hg38)
End
50485348/50018630 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01599
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/52119; hsa-mir-1185-1/Downstream/281225;
Nearest TSS
ENST00000550708/Upstream/7241; ENST00000426751/Downstream/20458;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/14929, chr14-CpG: 60/Downstream/97622
Upstream sequence
GCCAGGTGATCCTGACCTTGCACGTGCACTGCTGTTTATTCTTATAGTGGAAAAACGTTTCTCTGTATACTCATTGCCATCAAACGTGATTTCCCACACA
Downstream sequence
GGacttccctgactcctgaaggtatttgattttgcaacccctgATCTAAAGCGCCTTGATTAGCCTGGATTGTTTCAATCACAAGGGATGGAAGATAAAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate