Basic Information
VIS ID
TVIS44023624
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
52199520/51732802 (Hg38)
End
52199520/51732802 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/1432856; hsa-mir-1185-1/Downstream/2215625;
Nearest TSS
ENST00000550708/Upstream/15547; ENST00000557308/Downstream/17758;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/80032, chr14-CpG: 60/Downstream/256608
Nearby gene
FRMD6(+2076) ;
Upstream sequence
GGGTCTATAACATGAGCCCGAGCCATATAGACCAGGCAGGCTATCTGCTCCTGAACTGGTATGATCTACAGTTAGGATGGATCGGGTCTCCAGAGTGTCT
Downstream sequence
GGGTATATTGCATTTTGTTAGAATGACGTTTTCTTTTGCCAATAAAGCTGTCAGAGAGTGGACCAGTGTTTGAGTGGGGCAGTCAACTCACCATTTCAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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