Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene64499791643880316446345764422935644485576443700964439626644403696444223864420498644219926440975064410970644300836443023264443911
Basic Information
VIS ID
TVIS44023635
Fusion event
HTLV-1-MIR548AZ integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
64910629/64443911 (Hg38)
End
64910629/64443911 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA14B
Target gene
MIR548AZ
Nearest miRNA
hsa-mir-208a/Upstream/348786; hsa-mir-1185-1/Downstream/341715;
Nearest TSS
ENST00000550708/Upstream/1673; ENST00000557370/Downstream/4646;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/55605, chr14-CpG: 62/Downstream/21250
Upstream sequence
TCCCATAATGCTGTGCATGGAGGGGAACATTTGCACATATGGCTCTGTCAAGAGAGTAGGCCTCCTGCTCTCATTAGCTTGCTGACGGGAAGCTACCTGT
Downstream sequence
AAGGTCCTTGCTTCTTGCTCTGCCTCCACACAGCCCCTTCTGGAGTTGGAGCACATAGTCTCACTGCAATGGAAGAGGGCAGAGCTTCTTAATCACTATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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