VISDB Viral Integration Site DataBase

VIS ID

TVIS44023641

Fusion event

HTLV-1-SLC39A9 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

69894101/69427384 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-3613-3p ; hsa-mir-8080 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-545-3p ; hsa-mir-6792-5p ; hsa-mir-6838-5p ; hsa-mir-203a-3p ; hsa-mir-218-1-3p ; hsa-mir-224-3p ; hsa-mir-522-3p ; hsa-mir-510-3p ; hsa-mir-659-3p ; hsa-mir-2052 ; hsa-mir-3679-3p ; hsa-mir-3591-5p ; hsa-mir-8066 ; hsa-mir-151a-5p ; hsa-mir-151b ; hsa-mir-3150b-3p ; hsa-mir-4784 ; hsa-mir-634 ; hsa-mir-1226-3p ; hsa-mir-4530 ; hsa-mir-5584-5p ; hsa-mir-6873-5p ; hsa-mir-432-3p ; hsa-mir-485-5p ; hsa-mir-218-5p ; hsa-mir-192-3p ; hsa-mir-891b ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-3975 ; hsa-mir-142-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-4280 ; hsa-mir-133a-5p ; hsa-mir-3117-5p ; hsa-mir-4490 ; hsa-mir-5190 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4684-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-520f-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6832-3p ; hsa-mir-4691-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-888-5p

Nearest miRNA

hsa-mir-208a/Upstream/1985454; hsa-mir-1185-1/Downstream/3089436;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/29028, chr14-CpG: 142/Downstream/56358

Upstream sequence

tgagccactgtacccagccAGAGTAATTTTGTGGTGTCatttgaaaacagattacaaagtgctttataagtctcttctgaaaataagcattctggtctct

Downstream sequence

ttaacctttcatcatagattagtttccagccctAAGTCATTTAaattttttaaaaaatattttcatttatatatttatcattcacactttaggtgtacac