VISDB Viral Integration Site DataBase

VIS ID

TVIS44023644

Fusion event

HTLV-1-SMOC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q24.2

Reference genome

Start

End

70398968/69932251 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1260b ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-548t-5p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-548az-5p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6875-5p ; hsa-mir-4419a ; hsa-mir-3126-5p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-5582-3p ; hsa-mir-3689f ; hsa-mir-3689e ; hsa-mir-3689b-5p ; hsa-mir-3689a-5p ; hsa-mir-6735-3p ; hsa-mir-6811-3p ; hsa-mir-4679 ; hsa-mir-361-3p ; hsa-mir-6793-3p ; hsa-mir-4650-5p ; hsa-mir-1306-5p ; hsa-mir-500b-3p ; hsa-mir-495-3p ; hsa-mir-4477a ; hsa-mir-548n ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-6730-3p ; hsa-mir-4761-5p ; hsa-mir-888-3p ; hsa-mir-624-3p ; hsa-mir-5584-3p ; hsa-mir-4446-5p ; hsa-mir-6875-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-3156-3p ; hsa-mir-188-3p ; hsa-mir-6830-3p ; hsa-mir-3124-3p ; hsa-mir-6832-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-1264 ; hsa-mir-6507-3p ; hsa-mir-204-5p ; hsa-mir-211-5p

Nearest miRNA

hsa-mir-208a/Upstream/2490321; hsa-mir-1185-1/Downstream/2584569;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/52441, chr14-CpG: 16/Downstream/113824

Upstream sequence

TTCACCACTACCCTCTGTGTTTCGCAAAACACGAGTCCACCAGCGGGGTGCTTTGTTTTGCCTGCAGATGTGTGAAGCCACAGGCACAGCCCCTGAACAG

Downstream sequence

GAACAGCTTCCTGAAGGGCTCAGGAGGGGGTCAGTGGCTTTATAGTAAACTTGCTGTTTTGCTGTAGAATGCACGACTATGTTACAGGTGATGAGCTTCC