Basic Information
VIS ID
TVIS44023648
Fusion event
HTLV-1-YLPM1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
75265686/74798983 (Hg38)
End
75265686/74798983 (Hg38)
Orient
+
Location type
Exonic
Target gene
YLPM1
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-208a/Upstream/318779; hsa-mir-1185-1/Downstream/2467235;
Nearest TSS
ENST00000550708/Upstream/17598; ENST00000547879/Downstream/10649;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/35331, chr14-CpG: 58/Downstream/82799
Upstream sequence
GAGAAGAGCGAGGGCATGAAGAGTTTCCATTAGATGGTAGAAATGCTCCAATGGAACGAGAAAGACTCGATGACTGGGATAGAGAGAGATACTGGAGAGA
Downstream sequence
ATGTGAACGTGACTATCAAGATGATACACTAGAGCTCTATAACAGAGAGGACAGGTTCTCAGCACCACCATCTCGGTCTCATGATGGAGATAGGCGAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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