Basic Information
VIS ID
TVIS44023689
Fusion event
HTLV-1-TMCO5A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
38251088/37958887 (Hg38)
End
38251088/37958887 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMCO5A
miRNAs that regulate target gene
hsa-mir-4256 ; hsa-mir-513a-5p ; hsa-mir-4764-3p ; hsa-mir-345-5p ; hsa-mir-1972 ; hsa-mir-28-3p ; hsa-mir-6750-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/985986; hsa-mir-10393/Downstream/3732698;
Nearest TSS
ENST00000557528/Upstream/23630; ENST00000559992/Downstream/25879;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/467967, chr15-CpG: 36/Downstream/113907
Nearby gene
TMCO5A(+7465) ;
Upstream sequence
taaatcattctactaaaaagacacatgcacacgtatgtttactgtggcactgttcacaatagcaaagacttggaaccaacccaaatgctcatcaatgata
Downstream sequence
cactggataaagaaaatgtggcacatatacaccatggactactatgcagccataaaaaaggatgagttcatgtactttgcagggccatggatgaagctgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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