Basic Information
VIS ID
TVIS44023695
Fusion event
HTLV-1-LOC105370803 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
46920997/46628799 (Hg38)
End
46920997/46628799 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370803
Nearest miRNA
hsa-mir-10393/Upstream/1195670; hsa-mir-11181/Downstream/2540271;
Nearest TSS
ENST00000557528/Upstream/923604; ENST00000559148/Downstream/64489;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/923593, chr15-CpG: 96/Downstream/555373
Nearby gene
SEMA6D(+555406) ;
Upstream sequence
ATGTTGAGTTCTGGGAAACTGCATAAGTTCTGGAAATTTTTCATCTGTAATTTATTTTGTTTTTATGTCAAGTATTATGTTGCACATTTGTTTGTTTTGA
Downstream sequence
GGTATATGTTGAAAGGAGAAGATAATGGAAATATATTTACAATTGTAAAGCCAGAAATCTGCTACTTTCTTCAGTTTATAACTTTAGTTGAACatattaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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