VISDB Viral Integration Site DataBase

VIS ID

TVIS44023699

Fusion event

HTLV-1-ARPP19 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q21.2

Reference genome

Start

End

52856463/52564266 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-451a ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-92a-3p ; hsa-let-7b-5p ; hsa-mir-218-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-630 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-5681b ; hsa-mir-508-3p ; hsa-mir-4740-3p ; hsa-mir-4328 ; hsa-mir-205-3p ; hsa-mir-606 ; hsa-mir-544b ; hsa-mir-758-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-377-5p ; hsa-mir-6086 ; hsa-mir-4742-3p ; hsa-mir-4699-3p ; hsa-mir-1183 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-1238-3p ; hsa-mir-3124-3p ; hsa-mir-670-3p ; hsa-mir-6501-3p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3678-3p ; hsa-mir-6735-5p ; hsa-mir-7843-3p ; hsa-mir-127-5p ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-2467-3p ; hsa-mir-3622b-5p ; hsa-mir-496 ; hsa-mir-3616-3p ; hsa-mir-4786-3p ; hsa-mir-4761-3p ; hsa-mir-6833-5p ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-3911 ; hsa-mir-3190-3p ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-561-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-3606-5p ; hsa-mir-3935 ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-802 ; hsa-mir-577 ; hsa-mir-651-3p ; hsa-mir-548n ; hsa-mir-488-3p ; hsa-mir-374b-3p ; hsa-mir-4477b ; hsa-mir-4477a ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-5186 ; hsa-mir-10b-3p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-4791 ; hsa-mir-3201 ; hsa-mir-4252 ; hsa-mir-181a-2-3p ; hsa-mir-490-5p ; hsa-mir-3922-5p ; hsa-mir-487b-3p ; hsa-mir-4717-5p ; hsa-mir-513b-3p ; hsa-mir-4753-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-125b-2-3p ; hsa-mir-449b-3p ; hsa-mir-28-3p ; hsa-mir-5582-3p ; hsa-mir-708-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-1182 ; hsa-mir-1178-5p ; hsa-mir-4457 ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-7844-5p ; hsa-mir-510-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3942-3p ; hsa-mir-6808-3p ; hsa-mir-7973 ; hsa-mir-3189-5p ; hsa-mir-1225-3p ; hsa-mir-6759-3p ; hsa-mir-203a-3p ; hsa-mir-4501 ; hsa-mir-4323 ; hsa-mir-1200 ; hsa-mir-6895-3p ; hsa-mir-6845-3p ; hsa-mir-4324 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1252-3p ; hsa-mir-1275 ; hsa-mir-3662 ; hsa-mir-3976 ; hsa-mir-4525 ; hsa-mir-4665-5p ; hsa-mir-4698 ; hsa-mir-4723-5p ; hsa-mir-5010-5p ; hsa-mir-5698 ; hsa-mir-6134 ; hsa-mir-625-5p ; hsa-mir-6510-5p ; hsa-mir-6757-5p ; hsa-mir-6758-5p ; hsa-mir-6792-5p ; hsa-mir-6856-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-7854-3p ; hsa-mir-1273g-3p ; hsa-mir-1827 ; hsa-mir-3612 ; hsa-mir-4257 ; hsa-mir-4459 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6807-5p ; hsa-mir-6840-3p

Nearest miRNA

hsa-mir-10393/Upstream/287066; hsa-mir-11181/Downstream/2808674;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/34824, chr15-CpG: 67/Downstream/4289

Upstream sequence

TTAAAAACTTTTCTGAGGTTTACCTCTAGGCTGTTAGGAATCGATGGTTGCAGAGACCAAGGGAGCATGTTGTGTTCACTCTGAATAGAAATAGAAAACA

Downstream sequence

TGGATGAGgcggttgctcacacctgcagtcccagctacttggaggctgaggtgggaggctaggtgaacccaggagttcaaggcggcaatatgctatcatt