Basic Information
VIS ID
TVIS44023706
Fusion event
HTLV-1-DNAAF4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
55791755/55499557 (Hg38)
End
55791755/55499557 (Hg38)
Orient
+
Location type
Intronic
Target gene
DNAAF4
Nearest miRNA
hsa-mir-10393/Upstream/126523; hsa-mir-11181/Downstream/3671626;
Nearest TSS
ENST00000557528/Upstream/956; ENST00000561155/Downstream/8677;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/1001, chr15-CpG: 148/Downstream/88037
Upstream sequence
atgcacctttgttttacacctaaggcttcaactccccagtttgcaaactgttccctgaaatagttgctttgctccaaattcctcttcagaaaacgtttgt
Downstream sequence
tcacaACACATACCAGGAGCTTGTCTAAAACTATTGTATCCTGCAAATCCTATTAACTGTAAGGCCGCCAAAAGCACCTATATAGGTTTTGCTCCAAAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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