Basic Information
VIS ID
TVIS44023707
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
58223882/57931684 (Hg38)
End
58223882/57931684 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/2558650; hsa-mir-11181/Downstream/1239499;
Nearest TSS
ENST00000557528/Upstream/185577; ENST00000559684/Downstream/23585;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/224497, chr15-CpG: 148/Downstream/133427
Nearby gene
ALDH1A2(-21740) ;
Nearest cancer related gene
ALDH1A2(TSG, -21740) ;
Upstream sequence
cctccttttcttcttttcttcccttcctccatctttcccttctttcttGTAAGTTTCTTTTCTTCCCTTCCTCCATCTCTCCCTTCTTTCTTGTAAGTTA
Downstream sequence
TGCCCAGTCTCAAGTGTCTGAAATCTGAGGTGTATGAAATCTTCTCATCCCACATGTTAGTAGCTAGGGGGCTCCCTCACATTCCCCTCCACTTCCCCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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