Basic Information
VIS ID
TVIS44023710
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
62364789/62072590 (Hg38)
End
62364789/62072590 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA15A
Nearest miRNA
hsa-mir-10393/Upstream/2901328; hsa-mir-11181/Downstream/232068;
Nearest TSS
ENST00000557528/Upstream/5613; ENST00000561701/Downstream/92693;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/3794, chr15-CpG: 193/Downstream/91226
Nearby gene
C2CD4A(+1673) ;
Upstream sequence
ACATTCTCCCCATATCCATCCCCAGCACTTAGTTTAACCATGGCATTTAAGAAACTGTTCTGCCTCCAGGCTTTTGAGTTCACAGAAAAAACAGATGCAC
Downstream sequence
GACAGCCCATGGTGTTTTGAAACCCAAGTTTTACTATTCTGTACATTCACGTAGCAAAATCCCATCAAATTAATGTCATAGACATTATAAGCCCATAATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate