Basic Information
VIS ID
TVIS44023745
Fusion event
HTLV-1-C15orf32 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
93019537/92476307 (Hg38)
End
93019537/92476307 (Hg38)
Orient
-
Location type
Intronic
Target gene
C15orf32
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10393/Upstream/2469466; hsa-mir-1302-10/Downstream/428092;
Nearest TSS
ENST00000557528/Upstream/4386; ENST00000607766/Downstream/94505;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/81016, chr15-CpG: 97/Downstream/178837
Upstream sequence
acaccactgagagccagcaatgaactacgcctgctgtggacgttgtaggacacacagtccctgcctcaggaagctcaagtctaaggggggaacaattatg
Downstream sequence
cacagccaatggcagaatgaaataaagaggaaatgccaatccaaccaactgagggggttcagaggattcacagagaaggtgatagataagctggaccttg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate