Basic Information
VIS ID
TVIS44023772
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
26458881/26447560 (Hg38)
End
26458881/26447560 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA16E
Nearest miRNA
hsa-mir-1225/Upstream/422250; hsa-mir-11401/Downstream/1943422;
Nearest TSS
ENST00000527434/Upstream/125048; ENST00000562900/Downstream/147253;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/754250, chr16-CpG: 34/Downstream/662130
Nearby gene
HS3ST4(+309872) ;
Upstream sequence
gtaatcatttactgcccctcaatagaattcttcttctccccgccctcacaacctgtttcactgggatccaagctcccattttttctgaaatctcaaggtg
Downstream sequence
gtatatatgcttccagaccttattgttgggttgggtctttattctgaaggtgcccacatatatatgtttaataaatttgtatgccttttctcctactaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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