VISDB Viral Integration Site DataBase

VIS ID

TVIS44023788

Fusion event

HTLV-1-NKD1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q12.1

Reference genome

Start

End

50663363/50629452 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-5702 ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-548p ; hsa-mir-6873-5p ; hsa-mir-583 ; hsa-mir-7151-3p ; hsa-mir-6807-5p ; hsa-mir-5095 ; hsa-mir-5186 ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-6749-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-498 ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-6728-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p ; hsa-mir-6854-5p ; hsa-mir-216b-5p ; hsa-mir-195-5p ; hsa-mir-501-5p ; hsa-mir-532-5p ; hsa-mir-744-5p ; hsa-mir-1199-5p ; hsa-mir-1249-5p ; hsa-mir-147a ; hsa-mir-3911 ; hsa-mir-4693-3p ; hsa-mir-4779 ; hsa-mir-5581-3p ; hsa-mir-574-5p ; hsa-mir-6077 ; hsa-mir-644a ; hsa-mir-6751-3p ; hsa-mir-6797-5p ; hsa-mir-6847-5p ; hsa-mir-6867-5p ; hsa-mir-6872-3p ; hsa-mir-9500 ; hsa-mir-1304-3p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-3664-5p ; hsa-mir-4430 ; hsa-mir-4639-3p ; hsa-mir-6794-3p

Nearest miRNA

hsa-mir-1225/Upstream/336777; hsa-mir-11401/Downstream/112853;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/49662, chr16-CpG: 71/Downstream/43928

Upstream sequence

cattgggggttagggcttcaacctgtggatttgcaagtgagtggggagccacagtttagcccatagcaGGGACACATCTCCCTTTCCATTTTTCATTTCG

Downstream sequence

AACCCGAagcagatgctgttgatgcccccactccattttccctgggtccacctcaaagttcacctgctgccatggtggatggtgccCACTGTAAGAGCTT