Basic Information
VIS ID
TVIS44023805
Fusion event
HTLV-1-BEAN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
66523832/66489929 (Hg38)
End
66523832/66489929 (Hg38)
Orient
-
Location type
Intronic
Target gene
BEAN1
Nearest miRNA
hsa-mir-1225/Upstream/8717577; hsa-mir-11401/Downstream/712392;
Nearest TSS
ENST00000527434/Upstream/4125; ENST00000568560/Downstream/19508;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/61619, chr16-CpG: 90/Downstream/59404
Upstream sequence
TCCAGGGGGATCTATTTTCGAGTAGAACTCCAACTGGGATGCAGTTTCTCAATCAAAGGGATATGAACTGCCCTGGCCACTGAATTCAGAGAACATTGTA
Downstream sequence
GGGGGCAGGGGAGTTGGGAGCAGGGAGCAGAGATCCCAGCTGTGACGAGCCCAGGTCTGAGGCAGCTCCAAGACCAAGCACCCAGGTGGCTGTCCTTCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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