Basic Information
VIS ID
TVIS44023807
Fusion event
HTLV-1-C16orf47 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
73405770/73371871 (Hg38)
End
73405770/73371871 (Hg38)
Orient
+
Location type
Intronic
Target gene
C16orf47
Nearest miRNA
hsa-mir-1225/Upstream/3341449; hsa-mir-11401/Downstream/3497065;
Nearest TSS
ENST00000527434/Upstream/139109; ENST00000561875/Downstream/14934;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/304979, chr16-CpG: 74/Downstream/924764
Nearby gene
LINC01568(No orient, 14934)
Upstream sequence
TATTGCTGCCTGGTTTGGGGCCCTGAAGTCAATGTCACTGGTAAATAGTTCAAAGTCTCTCTTGCTGATCGCAATGCCCTTTCCCTCCCATTCAAGGTCT
Downstream sequence
CGGCCCAGCCCCTCTGGGCAAGCAGTTAAGATTTTCAGTGGCTATGAGCCCCCTTCCTGGACCTCTTCACTCTTTTTCAAGCCTAAACATCAGTGCTGCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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