VISDB Viral Integration Site DataBase

VIS ID

TVIS44023821

Fusion event

HTLV-1-PLCG2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q23.3

Reference genome

Start

End

81927385/81893780 (Hg38)

Orient

-

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-6771-5p ; hsa-mir-425-3p ; hsa-mir-6726-3p ; hsa-mir-1294 ; hsa-mir-542-3p ; hsa-mir-8065 ; hsa-mir-4710 ; hsa-mir-6747-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-8053 ; hsa-mir-6717-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-3202 ; hsa-mir-3194-5p ; hsa-mir-5589-3p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6875-5p ; hsa-mir-3126-5p ; hsa-mir-3179 ; hsa-mir-6746-5p ; hsa-mir-1249-3p ; hsa-mir-1224-3p ; hsa-mir-1288-5p ; hsa-mir-4717-3p ; hsa-mir-6890-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-383-5p ; hsa-mir-504-5p ; hsa-mir-4802-3p ; hsa-mir-5683 ; hsa-mir-6732-3p ; hsa-mir-3674 ; hsa-mir-6875-3p ; hsa-mir-4452 ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-4703-3p ; hsa-mir-4680-3p

Nearest miRNA

hsa-mir-1225/Upstream/282372; hsa-mir-11401/Downstream/795151;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/113823, chr16-CpG: 35/Downstream/117501

Upstream sequence

ACACGGCCACCTGCCTTCTCTCCTGCAGGTACCTTACAGGTGACCAGCTGCGGAGCGAGTCGTCCCCAGAAGCTTACATCCGCTGCCTGCGCATGGGCTG

Downstream sequence

TCGCTGCATTGAACGTGAGTAGCTCCTTCTTGGTGGAGGTCAGGCTCGCAGCAAATTGAGGATAACCATGTGGTTGCTCCATGTTTTCTTTCGAATTGTA