VISDB Viral Integration Site DataBase

VIS ID

TVIS44023832

Fusion event

HTLV-1-DNAH9 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

11567590/11664273 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-665 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-5582-5p ; hsa-mir-499b-3p ; hsa-mir-499a-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4451 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4468 ; hsa-mir-6840-3p ; hsa-mir-4459 ; hsa-mir-4756-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-129-5p ; hsa-mir-4524a-3p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-4797-5p ; hsa-mir-5007-5p ; hsa-mir-7855-5p

Nearest miRNA

hsa-mir-1253/Upstream/3477269; hsa-mir-10226/Downstream/417626;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/65262, chr17-CpG: 67/Downstream/332852

Upstream sequence

TCCTTTCCTTGAAGCCCAAACTTTGTTACCATGGTGATGCTTGGATGCCAATAGGTCAAGAGTGTATCATGTAAAAGAGAAGGCGGGGAGGAAGGAGGGg

Downstream sequence

agagagagagagagagtgagagagagagagagagaAACATTTTTTATTTATTTGTGTGCATTTTCTAAATCACTCAGTAGGATTGAATGCCAACTGCAAA