Basic Information
VIS ID
TVIS44023853
Fusion event
HTLV-1-GGNBP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
34914063/36558223 (Hg38)
End
34914063/36558223 (Hg38)
Orient
-
Location type
Intronic
Target gene
GGNBP2
Nearest miRNA
hsa-mir-1180/Upstream/4208021; hsa-mir-10226/Downstream/475522;
Nearest TSS
ENST00000595228/Upstream/12719; ENST00000619573/Downstream/18434;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/12622, chr17-CpG: 95/Downstream/33400
Nearest cancer related gene
GGNBP2(TSG, No orient, 0)
Upstream sequence
agaaGAGCgactgggcgcggtggctcacgcctataatcccaacactttgggaggccgaggcagttggattgcctgagctcaggagttcaagactagcctg
Downstream sequence
ggcaacacgctgaaaccgagtctctactaaaaatacaaaaaattagccaggagtggtggcgggtccctgtaatcccagctactcgagaggctgaggcagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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