Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene40041196399532633997776639980797399979603997845039982491399523683995396039966742399681773995854839959493399699133997066139972168399727103996394839964135399629553996301439996782
Basic Information
VIS ID
TVIS44023856
Fusion event
HTLV-1-PSMD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38153035/39996782 (Hg38)
End
38153035/39996782 (Hg38)
Orient
-
Location type
Intronic
Target gene
PSMD3
miRNAs that regulate target gene
hsa-mir-760 ; hsa-mir-769-5p ; hsa-mir-92b-3p ; hsa-mir-378a-5p ; hsa-mir-186-5p ; hsa-mir-92a-3p ; hsa-mir-6763-5p ; hsa-mir-6825-5p ; hsa-mir-3150a-3p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-7106-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-765 ; hsa-mir-4731-5p ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-181d-3p ; hsa-mir-224-5p ; hsa-mir-625-5p ; hsa-mir-6721-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6859-3p ; hsa-mir-612 ; hsa-mir-6860 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-939-3p ; hsa-mir-4292 ; hsa-mir-6791-5p ; hsa-mir-6814-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-1276
Nearest miRNA
hsa-mir-1180/Upstream/270221; hsa-mir-10226/Downstream/29550;
Nearest TSS
ENST00000595228/Upstream/3784; ENST00000582798/Downstream/17847;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/15545, chr17-CpG: 19/Downstream/57732
Upstream sequence
gtcttgcttgcttcacagggttggtaagattaaaagaagtccctgtattgaggcacttagcgaagtctaaattgtaaaaaagatgGCGCTGGTATCTAGC
Downstream sequence
TCCACAAAAGGGTGAGCCCTTATCCTCAGTTAAGCACTGAGTTTGGCGCTGTTACTATTTGCTTGCCATGTTTTTTTCTGGTCTCCTCCGAGGAAACTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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