Basic Information
VIS ID
TVIS44023872
Fusion event
HTLV-1-LOC101929185 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
56070894/57993533 (Hg38)
End
56070894/57993533 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA17B
Target gene
LOC101929185
Nearest miRNA
hsa-mir-10226/Upstream/1102178; hsa-mir-1250/Downstream/337699;
Nearest TSS
ENST00000595228/Upstream/54; ENST00000579991/Downstream/1317;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/4843, chr17-CpG: 139/Downstream/12910
Nearby gene
VEZF1(-5279) ;
Upstream sequence
TCCAGGCATAAAAGCAGGTGAAGGGGCCTGCTGCGCTGGTTATTAAAAGCTCTACACATGGACAACAGCTGTACTCAGCATCTACTCTTTAAGCTGTGAA
Downstream sequence
TAACACATCAAGCTTACCTGCTGCTGTCCACAAATACTACTTGAAGCACTTCACCCTTGGTTGCCTGAGTAGTGGCAGAAAGCTCTCTGCTAGGCCTGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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