Basic Information
VIS ID
TVIS44023882
Fusion event
HTLV-1-ARSG integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
66388090/68391949 (Hg38)
End
66388090/68391949 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARSG
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-10226/Upstream/920364; hsa-mir-1250/Downstream/32502;
Nearest TSS
ENST00000595228/Upstream/44804; ENST00000590690/Downstream/8207;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/99558, chr17-CpG: 70/Downstream/65259
Upstream sequence
CCACCAGCTCCATGGACTGTGGGAGCCAAAGGCAAACAGAAACATTCTGCACTGTAGTCAATGGAGAGATTCTGCCTGGGGTTGTAGGTAGAGCCCTGGA
Downstream sequence
GAGGAGAAGGAGATGGCCAACAGGAGACGGAGCCTCAGAGCAGGTCCTTTCTGCAGCCCCCTTAGAGGGCGGATATCCCCCCAGCCCCTCAGATATCAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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