Basic Information
VIS ID
TVIS44023886
Fusion event
HTLV-1-MYO15B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
73619769/75623689 (Hg38)
End
73619769/75623689 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYO15B
Nearest miRNA
hsa-mir-10226/Upstream/125061; hsa-mir-1250/Downstream/160832;
Nearest TSS
ENST00000595228/Upstream/1807; ENST00000577948/Downstream/101;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/33433, chr17-CpG: 22/Downstream/7773
Upstream sequence
ccagcctgtgtgacagagggagacgggagcagcgaagaaagtaactgagtagccagtgcagtgatgtcttaagctgagagagacatcTTGAGCCAGCCCC
Downstream sequence
AGCCCATGGCCTAGCAGGGTTTCTCCAGGGCTTCAGACCCCAGGCTCACCGCTGCCATCCCTCACCCCACCTGCCCTTCCTGTCCCCACAGCTGTGCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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