Basic Information
VIS ID
TVIS44023894
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
77778566/79804767 (Hg38)
End
77778566/79804767 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/97518; hsa-mir-1250/Downstream/294061;
Nearest TSS
ENST00000595228/Upstream/3084; ENST00000576963/Downstream/18685;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/98, chr17-CpG: 462/Downstream/5243
Nearby gene
CBX8(-7651) ;
Nearest cancer related gene
CBX8(OG, -7651) ;
Upstream sequence
CGTCTTATTCATCCTGAGAGCCGCACTCCCTCATTTGCATAATAATGGCTTATCTAGAATAACACAGCAATCAGAGGCAAAATTAATTTTCTTCAGCTAG
Downstream sequence
TCCTTGAGATCCTAAAAACAGAGGAGGCTTATGGCAAGAAAAGCCGGTTTAGCAGAGGGTGTAGGGTTCCTGACCAGGACCAAGGAGAGAGAAAGTTTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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