VISDB Viral Integration Site DataBase

VIS ID

TVIS44023899

Fusion event

HTLV-1-NPLOC4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

79531987/81564961 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-423-5p ; hsa-mir-106b-5p ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-218-5p ; hsa-mir-1180-5p ; hsa-mir-1233-5p ; hsa-mir-1251-5p ; hsa-mir-1343-5p ; hsa-mir-138-5p ; hsa-mir-143-5p ; hsa-mir-149-3p ; hsa-mir-191-5p ; hsa-mir-194-3p ; hsa-mir-196a-3p ; hsa-mir-2110 ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3125 ; hsa-mir-3128 ; hsa-mir-3150a-3p ; hsa-mir-3157-5p ; hsa-mir-3165 ; hsa-mir-3175 ; hsa-mir-3616-3p ; hsa-mir-369-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-376b-5p ; hsa-mir-376c-5p ; hsa-mir-3916 ; hsa-mir-3928-3p ; hsa-mir-3937 ; hsa-mir-4267 ; hsa-mir-4436b-3p ; hsa-mir-4456 ; hsa-mir-4481 ; hsa-mir-450a-2-3p ; hsa-mir-4514 ; hsa-mir-4632-5p ; hsa-mir-4640-5p ; hsa-mir-4648 ; hsa-mir-4691-3p ; hsa-mir-4692 ; hsa-mir-4726-5p ; hsa-mir-4728-5p ; hsa-mir-4745-5p ; hsa-mir-4746-3p ; hsa-mir-4755-3p ; hsa-mir-4779 ; hsa-mir-5004-5p ; hsa-mir-503-5p ; hsa-mir-517-5p ; hsa-mir-545-3p ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-6499-3p ; hsa-mir-6501-3p ; hsa-mir-6721-5p ; hsa-mir-6731-5p ; hsa-mir-6735-5p ; hsa-mir-6741-3p ; hsa-mir-6763-5p ; hsa-mir-6776-5p ; hsa-mir-6778-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6810-5p ; hsa-mir-6817-3p ; hsa-mir-6825-5p ; hsa-mir-6857-5p ; hsa-mir-6859-5p ; hsa-mir-6862-3p ; hsa-mir-6873-3p ; hsa-mir-6878-5p ; hsa-mir-6879-5p ; hsa-mir-6880-5p ; hsa-mir-6883-5p ; hsa-mir-6894-5p ; hsa-mir-6895-5p ; hsa-mir-7110-3p ; hsa-mir-7114-3p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-7843-5p ; hsa-mir-7847-3p ; hsa-mir-7973 ; hsa-mir-8071 ; hsa-mir-8085 ; hsa-mir-92b-5p ; hsa-mir-939-5p ; hsa-mir-1273h-3p ; hsa-mir-3166 ; hsa-mir-4771

Nearest miRNA

hsa-mir-10226/Upstream/113773; hsa-mir-4525/Downstream/128796;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/12023, chr17-CpG: 66/Downstream/71640

Upstream sequence

ATTCTAGCATTTGTCCAGGGCCGTAGCTCCCGGGCACTCTGGTGCTCTCAGCTGCAGGGACTCAGGGCACTCGGGCTGCACGAGGCACCACGGTGCGTGA

Downstream sequence

GGAGTCCCTGCAGCAATGCTGACAGAAGGTTCTCACGAGTGGGGAATCGTTCAGGACCTGGTGACTGAGGGTCCGGAAGACACGCAATGCCTGCGGTCCG