VISDB Viral Integration Site DataBase

VIS ID

TVIS44023902

Fusion event

HTLV-1-WDR45B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

80588191/82630315 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-744-5p ; hsa-mir-766-3p ; hsa-mir-433-3p ; hsa-mir-548aw ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-648 ; hsa-mir-323a-3p ; hsa-mir-595 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-494-3p ; hsa-mir-1226-3p ; hsa-mir-1237-5p ; hsa-mir-1252-3p ; hsa-mir-139-3p ; hsa-mir-1470 ; hsa-mir-149-3p ; hsa-mir-1914-3p ; hsa-mir-3175 ; hsa-mir-3184-5p ; hsa-mir-3661 ; hsa-mir-423-5p ; hsa-mir-4283 ; hsa-mir-4446-5p ; hsa-mir-4488 ; hsa-mir-4535 ; hsa-mir-4667-3p ; hsa-mir-4685-5p ; hsa-mir-4697-5p ; hsa-mir-4728-5p ; hsa-mir-4755-5p ; hsa-mir-4761-3p ; hsa-mir-4800-5p ; hsa-mir-492 ; hsa-mir-5006-3p ; hsa-mir-5194 ; hsa-mir-600 ; hsa-mir-631 ; hsa-mir-637 ; hsa-mir-642a-5p ; hsa-mir-659-5p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6753-5p ; hsa-mir-6785-5p ; hsa-mir-6825-5p ; hsa-mir-6837-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-6852-5p ; hsa-mir-6861-3p ; hsa-mir-6883-5p ; hsa-mir-7851-3p ; hsa-mir-8071

Nearest miRNA

hsa-mir-10226/Upstream/393587; hsa-mir-4525/Downstream/37918;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/16490, chr17-CpG: 95/Downstream/17110

Upstream sequence

AACACAGATCTGACGGCATCTCCTTCCTGGCCACACGTTACCTGGCATTCAAGCCTCCCCCAGATCTGCCTCCCACCTCCCCCACCCAGCCTACCTCCCG

Downstream sequence

CCTCCCACCTCTTCCCTGTGTTCTGCCCTCCATTCCTGGATCTTTCGCCTTGAGCCCTCTTTCCTCAACCAACAGCGAGGTTAAGCTGGCACGAGGCACA