Basic Information
VIS ID
TVIS44023929
Fusion event
HTLV-1-FHOD3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
34130727/36550764 (Hg38)
End
34130727/36550764 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA18A
Target gene
FHOD3
miRNAs that regulate target gene
hsa-mir-1303
Nearest miRNA
hsa-mir-1-2/Upstream/616622; hsa-mir-122/Downstream/1106371;
Nearest TSS
ENST00000575820/Upstream/6213; ENST00000587493/Downstream/44022;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/252083, chr18-CpG: 17/Downstream/194897
Upstream sequence
aattcatcaataagtatttcatatttttatgtattttttaaaattccaatttcaaattgctcatttgtattttttagacatacaacttaattttatgtat
Downstream sequence
taatctagtattgtacaaccttgttaaactgacttattagttctactagcttttctgtagattccataggatcttctcagatgatcatgtcgtctgtgaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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