Basic Information
VIS ID
TVIS44023935
Fusion event
HTLV-1-DLGAP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
4453048/4453048 (Hg38)
End
4453048/4453048 (Hg38)
Orient
+
Location type
Intronic
Target gene
DLGAP1
Nearest miRNA
hsa-mir-6718/Upstream/567616; hsa-mir-1-2/Downstream/1387647;
Nearest TSS
ENST00000575820/Upstream/188415; ENST00000583985/Downstream/1974;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/572961, chr18-CpG: 169/Downstream/921
Upstream sequence
ATTGTATTTGCAGACTAATCTTAGAATGAAATATAGAGAAATAGATAGCTATAAATTTAAAAAAATCTATGTATGCAAGTACATTCTTCTTTACTCACAC
Downstream sequence
AAGGTAACTAACATTTTCTCTTAAGTAAATTAGTTTTTTAAAAATTCACAGAATTTTATATCTGCGACTAGGGGTATTGCAAGGCACTAACCAACTGAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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