Basic Information
VIS ID
TVIS44023937
Fusion event
HTLV-1-SLC14A2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
43234941/45654976 (Hg38)
End
43234941/45654976 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC14A2
Nearest miRNA
hsa-mir-1-2/Upstream/684810; hsa-mir-122/Downstream/1725520;
Nearest TSS
ENST00000575820/Upstream/39495; ENST00000644925/Downstream/32049;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/591004, chr18-CpG: 37/Downstream/120377
Upstream sequence
CCACAGCTGTGACATCAGTTTGGTTTCCAGGGCAGCACTGTGCTGAGTTGGGCCTCTGGGATGTCACCTCTGGCTAATGAGATAGAGCTGAATACCTTCT
Downstream sequence
GCCCACGATTCATTACCTGCAGCTTCCACGGAAGATGCTTCTGCTCCAGGCTCCTTGGCCTCTCTCCTCAGTTCCTGTACCCCTTCCTCAGAAACACCAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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