Basic Information
VIS ID
TVIS44023938
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
43734820/46154854 (Hg38)
End
43734820/46154854 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/1184688; hsa-mir-122/Downstream/1225642;
Nearest TSS
ENST00000575820/Upstream/28198; ENST00000587591/Downstream/18699;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/49973, chr18-CpG: 175/Downstream/18483
Nearby gene
C18orf25(No orient, 19168)
Upstream sequence
CTGCCCTCCTTTATATTTCAAGACCATGGTGGGAGGTAGAGCATGAAACCAGATCACCTTCTGGTGTGAAGATTTCAAGGGAGAAGTTGAGGTGGGAAGC
Downstream sequence
CTCACCAGGTATTCTCTTTAGGACTTGCCTGAGAGTAGATTCTGGGCTGCTCAGACAGGGcagcgctcctgtgactggttgaatagtctgtctacatttg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate