Basic Information
VIS ID
TVIS44023951
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
60688629/63021396 (Hg38)
End
60688629/63021396 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/4570238; hsa-mir-5011/Downstream/4060188;
Nearest TSS
ENST00000575820/Upstream/115109; ENST00000634673/Downstream/140473;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/304258, chr18-CpG: 236/Downstream/296874
Nearby gene
PHLPP1(+40953) ;
Nearest cancer related gene
PHLPP1(TSG, +40953) ;
Upstream sequence
GAGACAAGCCACATTACTTGATGAGAGTCTTGTTATACTTCATTATCAATTTTTCAGCTTtccatcatccattccacccattaatctatcatttcatcca
Downstream sequence
cctactcattattccgtcacatccagccagccagtcagtcaaccaaccgtcctttcttccatcccaaacttacttccatttatccatccaaccaaccTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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