Basic Information
VIS ID
TVIS44023956
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
63704542/66037306 (Hg38)
End
63704542/66037306 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/7586148; hsa-mir-5011/Downstream/1044278;
Nearest TSS
ENST00000575820/Upstream/116364; ENST00000581951/Downstream/534865;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/285902, chr18-CpG: 83/Downstream/1478694
Nearby gene
CDH7(+155340) ;
Upstream sequence
ATCTATTTGTCATTTCATGTTTGTTTATTTGCTTAAGCTCCTATTCCTTGGGTCTACTGGCTATTCTCGCAGTATATATTGTGGAGGGGCCAAAGACTAA
Downstream sequence
AGGGTGATCTGCATCACCTTGAAATAATTCAAGGAAACATGACTGAGTGAAATACAGGGTGGAAAGTCACAGCACAGATTTACTGTTATGTGGAATTTAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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