VISDB Viral Integration Site DataBase

VIS ID

TVIS44023958

Fusion event

HTLV-1-CD226 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr18

Cytoband

q22.2

Reference genome

Start

End

67565494/69898258 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-223-5p ; hsa-mir-190a-3p ; hsa-mir-511-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-5011-5p ; hsa-mir-6798-3p ; hsa-mir-6793-3p ; hsa-mir-323b-3p ; hsa-mir-4640-3p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-516b-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6516-3p ; hsa-mir-630 ; hsa-mir-6832-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-676-5p ; hsa-mir-16-1-3p ; hsa-mir-4709-5p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-1299 ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-744-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-4294 ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-6812-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-2681-5p ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-892a ; hsa-mir-1227-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-3612 ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4325 ; hsa-mir-4497 ; hsa-mir-4537 ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-5186 ; hsa-mir-550b-2-5p ; hsa-mir-6086 ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-7703 ; hsa-mir-7855-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-mir-1-2/Upstream/2816572; hsa-mir-548av/Downstream/2955063;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/428246, chr18-CpG: 80/Downstream/307027

Upstream sequence

ATCAGATGCTAGCACACCATGTGGAGAAATGAAAGAACATAAAAGAAATGAAAAAAAGGAGGAGAAATCGACTTTCATGTGAGCCCTTCTGGTCCCTGGG

Downstream sequence

AAGTAAGAGGCAGCGTGAATGCGTGTCCTCAGTGCTCACACGCACAACTGTTTTGTGTTTTTCTTCTTCTTCTCTCTGGATGCCGCCCCGTCCAATCTCA