Basic Information
VIS ID
TVIS44023961
Fusion event
HTLV-1-ZNF407 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72476812/74764856 (Hg38)
End
72476812/74764856 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF407
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1-2/Upstream/1911474;
Nearest TSS
ENST00000575820/Upstream/133836; ENST00000581829/Downstream/112342;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/166128, chr18-CpG: 23/Downstream/322831
Upstream sequence
ctactagtagcctactgttgaccagaagccttactgataacataaacaaccagttaataaatattgtatatattactctattctttaagcttgataaaag
Downstream sequence
aaattgttattaagaaaatcataagaaataggtgtattatttattaagtggaagtgaatccttataaaagtcttcattctcattatcttcacattaagta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate