Basic Information
VIS ID
TVIS44023969
Fusion event
HTLV-1-CYP4F23P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
15694409/15583598 (Hg38)
End
15694409/15583598 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
CYP4F23P
Nearest miRNA
hsa-mir-10395/Upstream/133990; hsa-let-7e/Downstream/2698479;
Nearest TSS
ENST00000633603/Upstream/58265; ENST00000590209/Downstream/30955;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/32051, chr19-CpG: 25/Downstream/889
Nearby gene
CYP4F22(+31281) ;
Upstream sequence
CAGGCGGGGAGGGCTTTGGGCAGGGTGGAGGTCCCATCGTGTAGTGGAGTCCTTGTCCTGACTGCACCTCCTCCCCGACAGGGAACACTTGCACCATCAG
Downstream sequence
CATCTTTGGGATCCATCACAACCCTTCAGTCTGGCCGGACCCGGAGGTGCTACCCCTTCCGCCTTCTCCATCCCGGGGCCTGGTCAGGGGAGGGGTCTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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