VISDB Viral Integration Site DataBase

VIS ID

TVIS44023972

Fusion event

HTLV-1-SLC35E1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

16665261/16554450 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-197-3p ; hsa-mir-3192-5p ; hsa-mir-1273f ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-5010-5p ; hsa-mir-6851-5p ; hsa-mir-4525 ; hsa-mir-3689d ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4802-5p ; hsa-mir-4532 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-3065-5p ; hsa-mir-6849-3p ; hsa-mir-330-3p ; hsa-mir-4293 ; hsa-mir-508-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6794-3p ; hsa-mir-6879-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4524a-3p ; hsa-mir-6773-3p ; hsa-mir-1304-3p ; hsa-mir-4639-3p ; hsa-mir-5007-5p ; hsa-mir-3664-5p ; hsa-mir-4797-5p ; hsa-mir-6836-3p ; hsa-mir-5591-3p ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6741-3p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p

Nearest miRNA

hsa-mir-10395/Upstream/1104842; hsa-let-7e/Downstream/1727627;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/11521, chr19-CpG: 142/Downstream/17396

Upstream sequence

ATGGACCAGACCACAGTGCATGGACAGACTCAGAAGACAAGTCCTTggccaggcgcagtggcttatgcctgtagttcaagtgctttgggaggcctaggcg

Downstream sequence

ggaggatcacttgaggctaggagttggagaccagactggacaaaatagagagaccccatatctacaTGTGTTAAGAAACAAATGAAGAggccaggtgtgg