Basic Information
VIS ID
TVIS44023976
Fusion event
HTLV-1-ABHD17A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1881548/1881549 (Hg38)
End
1881548/1881549 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA19B
Target gene
ABHD17A
Nearest miRNA
hsa-mir-1302-11/Upstream/65311; hsa-let-7e/Downstream/352513;
Nearest TSS
ENST00000633603/Upstream/1532; ENST00000588555/Downstream/36;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3627, chr19-CpG: 80/Downstream/3220
Upstream sequence
AGGCACCAGGGAGTAGGTGGCCTCCGGCGGCAGGAAGGCGAGCTTGGCAGCGATGCGGCCGGGGCAGGGCGGGCAGCAGAAGAGGCAGCAGAGCTCACTC
Downstream sequence
AGCGACAGCCCATTCATggcgggcgccgcccaggccgggcctccaccggggcccccgccAACAACGCCGCCCGGCCTGGCCCGGCAGGGGAGGGGTGGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate