Basic Information
VIS ID
TVIS44023978
Fusion event
HTLV-1-LOC105372310 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
20256085/20145276 (Hg38)
End
20256085/20145276 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372310
Nearest miRNA
hsa-mir-10395/Upstream/710118; hsa-let-7e/Downstream/253996;
Nearest TSS
ENST00000633603/Upstream/24452; ENST00000597083/Downstream/5272;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/92978, chr19-CpG: 19/Downstream/937082
Nearby gene
ZNF486(+21938) ;
Upstream sequence
acataaatCTAATGTTTTTATTTTACAAAGTTTAGAAATTGCCTCAAAACAATAAAAACTTCATCATCAGTAAGACCTCCCCAGTTTCCTTTCATCTTAA
Downstream sequence
CCTTAACTGCATCTGCCTGTGGGATCCCAGCTTTCCAGGGCTCTGTAGCTTCTCTCAGGATAAAGGCTTCTTCTATGGCTGGGGTGAGCAGGCTGAGACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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