VISDB Viral Integration Site DataBase

VIS ID

TVIS44023979

Fusion event

HTLV-1-ZNF85 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p12

Reference genome

Start

End

21125185/20942379 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-6761-5p ; hsa-mir-3924 ; hsa-mir-6892-5p ; hsa-mir-4746-3p ; hsa-mir-4518 ; hsa-mir-6777-3p ; hsa-mir-1266-5p ; hsa-mir-6823-5p ; hsa-mir-1246 ; hsa-mir-3141 ; hsa-mir-510-5p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-4694-3p ; hsa-mir-4666a-5p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-5589-3p ; hsa-mir-4289 ; hsa-mir-6841-5p ; hsa-mir-5580-3p ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-4749-3p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-1225-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-6887-3p ; hsa-mir-1470 ; hsa-mir-6769a-3p ; hsa-mir-6514-3p ; hsa-mir-6894-3p ; hsa-mir-4279 ; hsa-mir-502-5p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-6890-3p ; hsa-mir-6826-3p ; hsa-mir-3692-3p ; hsa-mir-4753-3p ; hsa-mir-3124-3p ; hsa-mir-4502 ; hsa-mir-130b-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-647 ; hsa-mir-4715-3p ; hsa-mir-4314 ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-4646-5p ; hsa-mir-3192-5p ; hsa-mir-204-3p ; hsa-mir-6504-5p ; hsa-mir-3064-5p

Nearest miRNA

hsa-mir-10395/Upstream/543025; hsa-let-7e/Downstream/14180321;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/890081, chr19-CpG: 19/Downstream/139979

Upstream sequence

ttacaggcacccacctccacacctggctaattttttgtattcttggtagagacggggtttcagtatgttggccagactggtcttgaactcctgacctcat

Downstream sequence

gatccacctgccttggcctcccaaagtgctgggattacagacgtgagccaccttgctggcctattatgtttttaaatcaggaagtataatgcctctgttc