Basic Information
VIS ID
TVIS44024001
Fusion event
HTLV-1-MIR1268A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3768918/3768920 (Hg38)
End
3768918/3768920 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA19B
Target gene
MIR1268A
Nearest miRNA
hsa-mir-1227/Upstream/1138127; hsa-let-7e/Downstream/192494;
Nearest TSS
ENST00000633603/Upstream/6215; ENST00000595916/Downstream/3291;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1467, chr19-CpG: 35/Downstream/1648
Upstream sequence
ccccctcctcactctgctccagccgcatgggcctcctcgctattctttcaatgcacgaggcgtggtcctgccccagggcctttgcacagcctgtgcctct
Downstream sequence
gcccagctccctccttccctagaccttctccctcccgcccccggtctctaccttcacgccagcctcccctcctccagaactccctattaaaattgcagcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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